ABSTRACT
Objective To understand the etiological characteristics of children’s respiratory viruses in Hai’an City. Methods The clinical data of 6 810 children with acute respiratory infection in our hospital from January 2018 to May 2020 was retrospectively analyzed. The antigens of seven common respiratory viruses were detected by direct immunofluorescence assay. Results (1) Of the 6 810 specimens tested, 957 were positive, with a total positive rate of 14.05%. Among them, the number of RSV (respiratory syncytial virus) positive cases was the largest, with a total of 524 cases, followed by ADV (adenovirus), PIVⅢ (parainfluenza virus Ⅲ), PIVⅠ (parainfluenza virus Ⅰ), IFA (influenza A), IFB (influenza B), and PIVⅡ (parainfluenza virus Ⅱ), accounting for 154 cases (16.09%), 80 cases (8.36%), 65 cases (6.69%), 58 cases (6.60%), 55 cases (5.75%), and 21 cases (2.19%), respectively. (2) There was no statistically significant difference in respiratory virus infection between different genders (χ2=3.218, P>0.05). (3) The positive rate of antigen detection in children aged 11 days to 1 year old (19.24%) was the highest, with the viral infection rate decreasing with age. (4) The positive rates of viruses were different in different diseases, of which the highest was upper respiratory tract infection (27.53%), followed by pneumonia (16.90%), and bronchiolitis (7.19%), and the lowest was asthmatic bronchitis (6.18%). RSV was the main virus in each disease. Conclusion RSV is the main virus of respiratory tract infection in children in Hai’an City. The positive rate of viral infection in children aged 11 days to 1 year old is the highest, mainly with upper respiratory tract infection.